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A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Frontiers of Medicine doi: 10.1007/s11684-023-1011-0

Abstract: and efficacy of nirmatrelvir/ritonavir (Paxlovid) therapy for hemodialysis-dependent patients with severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Keywords： Paxlovid     hemodialysis     SARS-CoV-2     viral load     chest CT scan    

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Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 193-198 doi: 10.1007/s11684-020-0772-y

Abstract: The aim of this study was to investigate the clinical characteristics of neonates born to SARS-CoV-2 infected mothers and increase the current knowledge on the perinatal consequences of COVID-19. Nineteen neonates were admitted to Tongji Hospital from January 31 to February 29, 2020. Their mothers were clinically diagnosed or laboratory-confirmed with COVID-19. We prospectively collected and analyzed data of mothers and infants. There are 19 neonates included in the research. Among them, 10 mothers were confirmed COVID-19 by positive SARS-CoV-2 RT-PCR in throat swab, and 9 mothers were clinically diagnosed with COVID-19. Delivery occurred in an isolation room and neonates were immediately separated from the mothers and isolated for at least 14 days. No fetal distress was found. Gestational age of the neonates was 38.6±1.5 weeks, and average birth weight was 3293±425 g. SARS-CoV-2 RT-PCR in throat swab, urine, and feces of all neonates were negative. SARS-CoV-2 RT-PCR in breast milk and amniotic fluid was negative too. None of the neonates developed clinical, radiologic, hematologic, or biochemical evidence of COVID-19. No vertical transmission of SARS-CoV-2 and no perinatal complications in the third trimester were found in our study. The delivery should occur in isolation and neonates should be separated from the infected mothers and care givers.

Keywords： coronavirus disease 2019     severe acute respiratory syndrome-associated coronavirus     maternal-infant infection    

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Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

Jaffar A. Al-Tawfiq,Ali S. Omrani,Ziad A. Memish

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 111-119 doi: 10.1007/s11684-016-0446-y

Abstract:

The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 brought back memoriesof the occurrence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002.clinical presentation of MERS-CoV ranges from mild and non-specific presentation to progressive and severeTravel-associated MERS infection remains low.

Keywords： coronavirus     MERS     Middle East respiratory syndrome    

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Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 776-785 doi: 10.1007/s11684-020-0820-7

Abstract: Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus

Keywords： coronavirus disease 2019     pediatrics     emergency     retrospective investigation     severe acute respiratory syndromecoronavirus 2    

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Middle East respiratory syndrome coronavirus: a comprehensive review

Mahmoud M. Shehata,Mokhtar R. Gomaa,Mohamed A. Ali,Ghazi Kayali

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 120-136 doi: 10.1007/s11684-016-0430-6

Abstract:

The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remainedCases have been mostly reported in the Middle East, however travel-associated cases and outbreaks haveThe infection is severe and highly fatal thus necessitating rapid and efficacious interventions.

Keywords： MERS     coronavirus     review    

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Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia

Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 126-130 doi: 10.1007/s11684-017-0603-y

Abstract: Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as an importantrespiratory disease with high fatality rates of 40%–60%.

Keywords： Middle East respiratory syndrome coronavirus     MERS-CoV     pregnancy     pediatrics    

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Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary

Tao Li, Nanfu Luo, Lei Du, Jin Liu, Lina Gong, Jing Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 296-301 doi: 10.1007/s11684-012-0219-1

Abstract: improved the development of modern cardiac surgery, many factors during CPB have been reported to induce acuterespiratory distress syndrome (ARDS).

Keywords： tumor necrosis factor-α     cardiopulmonary bypass     inflammation     acute respiratory distress syndrome    

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Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute RespiratoryDistress Syndrome

Xuan Zhao, Yi Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1073-1075 doi: 10.1016/j.eng.2020.05.015

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The Scientific Foundation of Chinese Herbal Medicine against COVID-19 Perspective

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Engineering 2020, Volume 6, Issue 10,   Pages 1099-1107 doi: 10.1016/j.eng.2020.08.009

Abstract: text-autospace:none">The recent coronavirusSupporting evidence shows that COVID-19 shares a genomic similarity with other coronaviruses, such as severeacute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome  coronaviruspathological features of COVID-19 patients, patients can suffer from five steps of progression, starting with severe

Keywords： Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus     Chinese herbal medicine     Antiviral    

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Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

Lingling Tang, Yingan Jiang, Mengfei Zhu, Lijun Chen, Xiaoyang Zhou, Chenliang Zhou, Peng Ye, Xiaobei Chen, Baohong Wang, Zhenyu Xu, Qiang Zhang, Xiaowei Xu, Hainv Gao, Xiaojun Wu, Dong Li, Wanli Jiang, Jingjing Qu, Charlie Xiang, Lanjuan Li

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 664-673 doi: 10.1007/s11684-020-0810-9

Abstract: The coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 was identified in December 2019.The symptoms include fever, cough, dyspnea, early symptom of sputum, and acute respiratory distress syndromeMesenchymal stem cell (MSC) therapy is the immediate treatment used for patients with severe cases of

Keywords： coronavirus disease 2019 (COVID-19)     mesenchymal stem cell     acute respiratory distress syndrome     stem cell    

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High-Throughput, Multi-Index Isothermal Amplification Platform for Rapid Detection of 19 Types of Common Respiratory Article

Wanli Xing, Yingying Liu, Huili Wang, Shanglin Li, Yongping Lin, Lei Chen, Yan Zhao, Shuang Chao, Xiaolan Huang, Shaolin Ge, Tao Deng, Tian Zhao, Baolian Li, Hanbo Wang, Lei Wang, Yunpeng Song, Ronghua Jin, Jianxing He, Xiuying Zhao, Peng Liu, Weimin Li, Jing Cheng

Engineering 2020, Volume 6, Issue 10,   Pages 1130-1140 doi: 10.1016/j.eng.2020.07.015

Abstract: quot;serif"">Fast and accurate diagnosis and the immediate isolation of patients infected with severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) are regarded as the most effective measures torestrain the coronavirus disease 2019 (COVID-19) pandemic.clinically diagnosed samples, and 614 cases of clinical samples from patients or suspected patients with respiratorytest results matched the referenced results well and reflected the epidemic characteristics of the respiratory

Keywords： Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus 2     Microfluidics     Nucleic acid    

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Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 302-305 doi: 10.1007/s11684-011-0145-7

Abstract: A treatment method based on drainage via retroperitoneal laparoscopy was adopted for 15 severe acute

Keywords： severe acute pancreatitis (SAP)     laparoscope     retroperitoneal drainage     treatment    

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Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Frontiers of Medicine doi: 10.1007/s11684-023-1041-7

Abstract: The coronavirus disease 2019 (COVID-19) epidemic has triggered a huge impact on healthcare, socioeconomicsSevere COVID-19 may be associated with an increased risk of stroke and increase the rates of disabilityand mortality, posing a serious challenge to acute stroke diagnosis, treatment, and care.

Keywords： SARS-CoV-2     ischemic stroke     stroke     hemorrhagic stroke     cerebral venous thrombosis     vaccination    

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Clinical factors associated with composition of lung microbiota and important taxa predicting clinicalprognosis in patients with severe community-acquired pneumonia

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 389-402 doi: 10.1007/s11684-021-0856-3

Abstract: Few studies have described the key features and prognostic roles of lung microbiota in patients with severestrongest independent association with lung microbiota (R2=0.033; P=0.018), followed by acuteincrease in α-diversity and the abundance of the families Prevotellaceae and Actinomycetaceae were associatedThe positive bacteria lab test results, AKI, and plasma MIP-1β level were associated with patients’ lung

Keywords： severe community-acquired pneumonia     lung microbiota     clinical improvements     7-category ordinal scale    

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Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 651-658 doi: 10.1007/s11684-021-0859-0

Abstract: To present the clinical characteristics and the misdiagnosis rate of acute coronary syndrome manifestedshowed that chest tightness, dyspnea, perspiring, and exertional throat symptoms were significantly associatedwith acute coronary syndrome, with odds ratios of 8.3 (95% CI 2.2−31.5), 10.9 (95% CI 1.8−66.9), 25.4A total of 25 (56.82%) out of 44 acute coronary syndrome patients, who were first admitted to the otorhinolaryngologyThroat discomfort can be the principal manifestation of acute coronary syndrome.

Keywords： acute coronary syndrome (ACS)     throat discomfort (TD)     throat pain     cardiology departments     non-cardiologic    

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Title Author Date Type Operation

A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus

Journal Article

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Journal Article

Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns

Jaffar A. Al-Tawfiq,Ali S. Omrani,Ziad A. Memish

Journal Article

Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19

Xiaofang Cai, Hanlan Jiang, Simin Zhang, Shengying Xia, Wenhui Du, Yaoling Ma, Tao Yu, Wenbin Li

Journal Article

Middle East respiratory syndrome coronavirus: a comprehensive review

Mahmoud M. Shehata,Mokhtar R. Gomaa,Mohamed A. Ali,Ghazi Kayali

Journal Article

Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia

Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish

Journal Article

Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary

Tao Li, Nanfu Luo, Lei Du, Jin Liu, Lina Gong, Jing Zhou

Journal Article

Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute RespiratoryDistress Syndrome

Xuan Zhao, Yi Zhang

Journal Article

The Scientific Foundation of Chinese Herbal Medicine against COVID-19

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Journal Article

Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19

Lingling Tang, Yingan Jiang, Mengfei Zhu, Lijun Chen, Xiaoyang Zhou, Chenliang Zhou, Peng Ye, Xiaobei Chen, Baohong Wang, Zhenyu Xu, Qiang Zhang, Xiaowei Xu, Hainv Gao, Xiaojun Wu, Dong Li, Wanli Jiang, Jingjing Qu, Charlie Xiang, Lanjuan Li

Journal Article

High-Throughput, Multi-Index Isothermal Amplification Platform for Rapid Detection of 19 Types of Common Respiratory

Wanli Xing, Yingying Liu, Huili Wang, Shanglin Li, Yongping Lin, Lei Chen, Yan Zhao, Shuang Chao, Xiaolan Huang, Shaolin Ge, Tao Deng, Tian Zhao, Baolian Li, Hanbo Wang, Lei Wang, Yunpeng Song, Ronghua Jin, Jianxing He, Xiuying Zhao, Peng Liu, Weimin Li, Jing Cheng

Journal Article

Treatment of severe acute pancreatitis through retroperitoneal laparoscopic drainage

Chun Tang, Baolin Wang, Bing Xie, Hongming Liu, Ping Chen

Journal Article

Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Journal Article

Clinical factors associated with composition of lung microbiota and important taxa predicting clinicalprognosis in patients with severe community-acquired pneumonia

Journal Article

Atypical manifestations of acute coronary syndrome — throat discomfort: a multi-center observational

Journal Article